:root{
  --ground:#F4F7F6; --surface:#FFFFFF; --ink:#0F242B; --muted:#51656B; --line:#D5DFDD;
  --teal:#007C8A; --teal-soft:#D2EFF0; --amber:#F2A516; --amber-soft:#FDEBC8;
  --hero:#052C3B; --hero-ink:#EAF3F1; --hero-muted:#A3C9CE;
  --display:"Manrope",ui-sans-serif,system-ui,sans-serif;
  --body:"Source Sans 3",system-ui,-apple-system,"Segoe UI",sans-serif;
  --mono:"IBM Plex Mono",ui-monospace,Menlo,monospace;
}
@media (prefers-color-scheme:dark){:root:not([data-theme="light"]){
  --ground:#0B1A1E; --surface:#112429; --ink:#E4EEEC; --muted:#93AAA8; --line:#22393E;
  --teal:#3FD8DE; --teal-soft:#15363B; --amber:#F0B23E; --amber-soft:#3A2E14;
  --hero:#031E29; --hero-ink:#EAF3F1; --hero-muted:#8FAEAB;}}
:root[data-theme="dark"]{
  --ground:#0B1A1E; --surface:#112429; --ink:#E4EEEC; --muted:#93AAA8; --line:#22393E;
  --teal:#3FD8DE; --teal-soft:#15363B; --amber:#F0B23E; --amber-soft:#3A2E14;
  --hero:#031E29; --hero-ink:#EAF3F1; --hero-muted:#8FAEAB;}
*{box-sizing:border-box}
html{scroll-behavior:smooth}
body{background:var(--ground);color:var(--ink);font-family:var(--body);font-size:16px;line-height:1.6;-webkit-font-smoothing:antialiased}
a{color:inherit}
:focus-visible{outline:2px solid var(--amber);outline-offset:3px;border-radius:4px}
.wrap{max-width:1180px;margin-inline:auto;padding-inline:clamp(16px,4vw,40px)}
h1,h2,h3{font-family:var(--display);text-wrap:balance;margin:0;letter-spacing:-.03em}
p{margin:0}
.eyebrow{font-family:var(--mono);font-size:12px;letter-spacing:.14em;text-transform:uppercase;color:var(--teal)}

/* nav */
header.nav{position:sticky;top:0;z-index:20;background:color-mix(in srgb,var(--hero) 88%,transparent);backdrop-filter:blur(10px);color:var(--hero-ink);border-bottom:1px solid rgba(255,255,255,.08)}
.nav .wrap{display:flex;align-items:center;justify-content:space-between;gap:16px;height:64px}
.logo{font-family:var(--display);font-weight:800;font-size:22px;letter-spacing:.02em;text-decoration:none;display:flex;align-items:center;gap:10px}
.logo i{width:12px;height:12px;border-radius:50%;background:var(--amber);box-shadow:0 0 0 4px rgba(242,165,22,.25)}
.nav ul{display:flex;gap:clamp(12px,2.5vw,32px);list-style:none;margin:0;padding:0;font-size:14px}
.nav ul a{text-decoration:none;color:var(--hero-muted);transition:color .2s}
.nav ul a:hover{color:var(--hero-ink)}
@media(max-width:640px){.nav ul li:not(:last-child){display:none}}

/* hero */
.hero{position:relative;background:var(--hero);color:var(--hero-ink);overflow:hidden}
#field{position:absolute;inset:0;width:100%;height:100%;opacity:.9}
.hero .wrap{position:relative;padding-block:clamp(72px,11vw,140px) clamp(56px,8vw,96px);display:grid;gap:28px}
.hero .eyebrow{color:var(--amber)}
.hero h1{font-size:clamp(40px,7vw,88px);font-weight:800;line-height:.98;max-width:13ch}
.hero h1 em{font-style:normal;color:var(--amber)}
.hero p.lede{font-size:clamp(17px,1.6vw,20px);color:var(--hero-muted);max-width:56ch}
.cta{display:flex;flex-wrap:wrap;gap:12px;margin-top:8px}
.btn{display:inline-flex;align-items:center;gap:8px;padding:12px 20px;border-radius:999px;font-weight:600;font-size:15px;text-decoration:none;transition:transform .2s,background .2s}
.btn.primary{background:var(--amber);color:#1A1204}
.btn.ghost{border:1px solid rgba(234,243,241,.3);color:var(--hero-ink)}
.btn:hover{transform:translateY(-2px)}
.legend{display:flex;flex-wrap:wrap;gap:20px;font-family:var(--mono);font-size:12px;color:var(--hero-muted);margin-top:24px}
.legend span{display:flex;align-items:center;gap:8px}
.legend b{width:9px;height:9px;border-radius:50%;display:inline-block}

/* stats strip */
.strip{background:var(--surface);border-bottom:1px solid var(--line)}
.strip .wrap{display:grid;grid-template-columns:repeat(4,1fr);gap:0}
.strip .wrap>div{padding:28px 20px;border-left:1px solid var(--line)}
.strip .wrap>div:first-child{border-left:0;padding-left:0}
.strip strong{display:block;font-family:var(--display);font-size:clamp(28px,3.4vw,40px);font-weight:800;color:var(--teal);line-height:1.1}
.strip span{font-size:14px;color:var(--muted)}
@media(max-width:760px){.strip .wrap{grid-template-columns:1fr 1fr}.strip .wrap>div:nth-child(3){border-left:0;padding-left:0}.strip .wrap>div{border-top:1px solid var(--line)}.strip .wrap>div:nth-child(-n+2){border-top:0}}

section{padding-block:clamp(64px,9vw,112px)}
.sec-head{display:grid;gap:14px;margin-bottom:48px;max-width:760px}
.sec-head h2{font-size:clamp(30px,4.2vw,52px);font-weight:800;line-height:1.05}
.sec-head p{color:var(--muted);font-size:18px;max-width:62ch}

/* mission */
.mission{display:grid;grid-template-columns:1fr;gap:28px;align-items:start}
.mission .txt{max-width:68ch}
.mission blockquote{margin:0;font-family:var(--display);font-size:clamp(30px,4.2vw,52px);line-height:1.05;font-weight:800;letter-spacing:-.03em;text-wrap:balance}
.mission blockquote::before{content:"Mission";display:block;font-family:var(--mono);font-size:12px;letter-spacing:.14em;text-transform:uppercase;color:var(--amber);margin-bottom:16px;font-weight:400}
.mission .txt{display:grid;gap:16px;color:var(--muted);font-size:17px}
@media(max-width:820px){.mission{grid-template-columns:1fr}}

/* pipeline */
.pipe{background:var(--surface);border:1px solid var(--line);border-radius:18px;overflow-x:auto}
.pipe-grid{min-width:720px;display:grid;grid-template-columns:260px repeat(4,1fr)}
.pipe-grid>div{padding:18px 20px;border-bottom:1px solid var(--line)}
.ph{font-family:var(--mono);font-size:12px;letter-spacing:.1em;text-transform:uppercase;color:var(--muted);background:var(--ground)}
.prog{display:grid;gap:4px}
.prog h3{font-size:20px}
.prog small{color:var(--muted);font-size:13px}
.track{grid-column:span 4;display:flex;align-items:center;position:relative}
.bar{height:34px;border-radius:999px;display:flex;align-items:center;justify-content:flex-end;padding-inline:14px;font-family:var(--mono);font-size:12px;font-weight:500;color:#fff;background:linear-gradient(90deg,var(--teal) 0%,color-mix(in srgb,var(--teal) 70%,var(--amber)) 100%);animation:grow 1.4s cubic-bezier(.2,.8,.2,1) both}
.bar.pre{background:var(--teal);opacity:.75}
@keyframes grow{from{clip-path:inset(0 100% 0 0)}to{clip-path:inset(0 0 0 0)}}
.pipe-grid>div:nth-last-child(-n+2){border-bottom:0}
.partner{display:flex;gap:8px;flex-wrap:wrap;margin-top:6px}
.chip{font-family:var(--mono);font-size:11px;padding:3px 9px;border-radius:999px;background:var(--teal-soft);color:var(--teal)}
.chip.amber{background:var(--amber-soft);color:var(--amber)}

/* mechanism */
.mech{display:grid;grid-template-columns:1fr 1.15fr;gap:clamp(32px,5vw,72px);align-items:center;margin-top:72px}
.mech .txt{display:grid;gap:18px;color:var(--muted);font-size:17px}
.mech .txt h3{font-size:clamp(30px,4.2vw,52px);font-weight:800;line-height:1.05;color:var(--ink)}
.mech .txt strong{color:var(--ink)}
.trials{display:grid;gap:10px;margin-top:6px}
.trial{display:grid;grid-template-columns:auto 1fr;gap:4px 14px;padding:14px 16px;border:1px solid var(--line);border-radius:12px;background:var(--surface);font-size:14px}
.trial b{font-family:var(--mono);font-weight:500;color:var(--teal);font-size:12px;grid-row:span 2;align-self:center}
.trial a{font-family:var(--mono);font-size:12px;color:var(--muted)}
.diagram{background:var(--hero);border-radius:20px;padding:16px;aspect-ratio:5/4;max-width:100%}
.diagram svg{width:100%;height:100%;display:block}
@media(max-width:860px){.mech{grid-template-columns:1fr}}

/* timeline */
.timeline{position:relative;display:grid;grid-template-columns:repeat(6,1fr);gap:16px}
.timeline::before{content:"";position:absolute;left:0;right:0;top:9px;height:2px;background:var(--line)}
.tl{position:relative;display:grid;gap:8px;padding-top:32px}
.tl::before{content:"";position:absolute;top:2px;left:0;width:16px;height:16px;border-radius:50%;background:var(--ground);border:3px solid var(--teal)}
.tl.hot::before{border-color:var(--amber);background:var(--amber)}
.tl time{font-family:var(--display);font-size:28px;font-weight:800}
.tl p{font-size:14px;color:var(--muted)}
@media(max-width:900px){.timeline{grid-template-columns:1fr 1fr 1fr;row-gap:36px}}
@media(max-width:520px){.timeline{grid-template-columns:1fr}.timeline::before{display:none}}

/* news */
.news-sec{background:var(--surface);border-block:1px solid var(--line)}
.news{display:grid;grid-template-columns:1.3fr 1fr;gap:24px}
.feature{background:var(--hero);color:var(--hero-ink);border-radius:20px;padding:clamp(24px,4vw,44px);display:grid;gap:18px;align-content:end;min-height:340px;position:relative;overflow:hidden}
.feature::after{content:"";position:absolute;right:-80px;top:-80px;width:280px;height:280px;border-radius:50%;background:radial-gradient(circle,rgba(242,165,22,.5),transparent 65%)}
.feature .eyebrow{color:var(--amber)}
.feature h3{font-size:clamp(24px,3vw,36px);line-height:1.1;position:relative}
.feature p{color:var(--hero-muted);position:relative}
.list{display:grid;align-content:start}
.item{display:grid;grid-template-columns:96px 1fr;gap:16px;padding:18px 0;border-bottom:1px solid var(--line);text-decoration:none;transition:padding .2s}
.item:hover{padding-left:6px}
.item time{font-family:var(--mono);font-size:12px;color:var(--muted);padding-top:3px;font-variant-numeric:tabular-nums}
.item span{font-weight:500}
@media(max-width:820px){.news{grid-template-columns:1fr}}

/* team */
.team{display:grid;grid-template-columns:repeat(5,1fr);gap:16px}
@media(max-width:1080px){.team{grid-template-columns:repeat(3,1fr)}}
@media(max-width:640px){.team{grid-template-columns:1fr 1fr}}
.person{padding:16px}
.person{display:grid;gap:10px;padding:22px;border:1px solid var(--line);border-radius:16px;background:var(--surface);align-content:start}
.avatar{width:56px;height:56px;border-radius:50%;display:grid;place-items:center;font-family:var(--display);font-weight:800;font-size:19px;background:var(--teal-soft);color:var(--teal)}
.person h3{font-size:19px}
.role{font-family:var(--mono);font-size:11px;letter-spacing:.08em;text-transform:uppercase;color:var(--amber)}
.person p{font-size:14px;color:var(--muted)}
.meta{display:grid;grid-template-columns:repeat(3,1fr);gap:32px;margin-top:56px;padding-top:40px;border-top:1px solid var(--line)}
.meta h4{font-family:var(--mono);font-size:12px;letter-spacing:.14em;text-transform:uppercase;color:var(--teal);margin:0 0 14px;font-weight:500}
.meta ul{list-style:none;margin:0;padding:0;display:grid;gap:8px;font-size:15px}
.meta li small{color:var(--muted)}
@media(max-width:760px){.meta{grid-template-columns:1fr}}

/* contact */
.contact{background:var(--hero);color:var(--hero-ink)}
.contact .grid{display:grid;grid-template-columns:1.2fr 1fr;gap:48px;align-items:end}
.contact h2{font-size:clamp(34px,5vw,64px);font-weight:800;line-height:1}
.contact h2 em{font-style:normal;color:var(--amber)}
.coords{display:grid;gap:14px;font-size:16px}
.coords div{display:grid;gap:2px;padding-bottom:14px;border-bottom:1px solid rgba(234,243,241,.14)}
.coords small{font-family:var(--mono);font-size:11px;letter-spacing:.14em;text-transform:uppercase;color:var(--hero-muted)}
.coords a{text-decoration:none}
.coords a:hover{color:var(--amber)}
footer{background:var(--hero);color:var(--hero-muted);font-size:13px;border-top:1px solid rgba(234,243,241,.1)}
footer .wrap{display:flex;justify-content:space-between;flex-wrap:wrap;gap:12px;padding-block:24px}
@media(max-width:820px){.contact .grid{grid-template-columns:1fr}}
@media (prefers-reduced-motion:reduce){*{animation:none!important;transition:none!important}html{scroll-behavior:auto}}

/* ---- v1.1 additions ---- */
.li-follow{justify-self:start;display:inline-flex;align-items:center;gap:10px;margin-top:4px;padding:10px 16px;border:1px solid rgba(234,243,241,.3);border-radius:999px;font-weight:600;font-size:15px;text-decoration:none!important;color:var(--hero-ink);transition:background .2s,border-color .2s,transform .2s}
.li-follow:hover{background:rgba(234,243,241,.1);border-color:var(--amber);color:var(--amber)!important;transform:translateY(-2px)}
.li-follow svg{width:18px;height:18px;fill:currentColor}

.burger{display:none;width:42px;height:42px;border:1px solid rgba(234,243,241,.25);border-radius:10px;background:transparent;cursor:pointer;flex-direction:column;justify-content:center;align-items:center;gap:5px}
.burger span{display:block;width:18px;height:2px;background:var(--hero-ink);border-radius:2px;transition:transform .25s,opacity .25s}
.nav.open .burger span:nth-child(1){transform:translateY(7px) rotate(45deg)}
.nav.open .burger span:nth-child(2){opacity:0}
.nav.open .burger span:nth-child(3){transform:translateY(-7px) rotate(-45deg)}
.pipe-mobile{display:none}
@media(max-width:640px){
  .burger{display:flex}
  .nav ul{position:absolute;top:64px;left:0;right:0;flex-direction:column;gap:0;background:var(--hero);padding:8px 16px 20px;border-bottom:1px solid rgba(255,255,255,.08);display:none}
  .nav.open ul{display:flex}
  .nav ul li:not(:last-child){display:block!important}
  .nav ul a{display:block;padding:14px 4px;font-size:18px;font-family:var(--display);font-weight:700;color:var(--hero-ink);border-bottom:1px solid rgba(234,243,241,.08)}
  .pipe{display:none}
  .pipe-mobile{display:grid;gap:14px}
  .pcard{background:var(--surface);border:1px solid var(--line);border-radius:16px;padding:18px;display:grid;gap:10px}
  .pc-top{display:flex;justify-content:space-between;align-items:center;gap:10px}
  .pc-top h3{font-size:20px}
  .pcard small{color:var(--muted);font-size:13px}
  .stage{font-family:var(--mono);font-size:11px;letter-spacing:.08em;text-transform:uppercase;padding:4px 10px;border-radius:999px;background:var(--teal);color:var(--ground);white-space:nowrap}
  .stage.pre{background:var(--teal-soft);color:var(--teal)}
  .seg{display:grid;grid-template-columns:repeat(4,1fr);gap:4px}
  .seg i{height:8px;border-radius:4px;background:var(--line)}
  .seg i.on{background:var(--teal)}
  .seg i.half{background:linear-gradient(90deg,var(--teal) 50%,var(--line) 50%)}
  .seg-l{display:grid;grid-template-columns:repeat(4,1fr);font-family:var(--mono);font-size:10px;color:var(--muted);letter-spacing:.04em}
}

#pipeline .sec-head p strong{color:var(--ink);font-weight:600}
.pipe-cta{margin-top:28px;display:flex}
#view-programs .mech-head:first-child{margin-top:56px}
.inv{text-decoration:none;border-bottom:1px solid var(--line);transition:color .2s,border-color .2s}
.inv:hover{color:var(--teal);border-color:var(--teal)}
.partners-strip{display:grid;grid-template-columns:140px 1fr;gap:24px;align-items:center;margin-top:56px;padding-top:32px;border-top:1px solid var(--line)}
.logos{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:16px}
.logo-card{background:#fff;border:1px solid var(--line);border-radius:16px;padding:24px 28px 18px;display:grid;gap:14px;justify-items:center;transition:transform .2s,box-shadow .2s}
.logo-card:hover{transform:translateY(-2px);box-shadow:0 12px 30px -18px rgba(5,44,59,.4)}
.logo-card{grid-template-rows:88px auto;align-items:center}
.logo-card img{width:auto;max-width:100%;object-fit:contain}
.logo-card .lg-ip{height:80px}
.logo-card .lg-az{height:58px}
.logo-card small{font-family:var(--mono);font-size:11px;letter-spacing:.08em;text-transform:uppercase;color:#51656B}
@media(max-width:700px){.partners-strip{grid-template-columns:1fr}.logos{grid-template-columns:1fr}}

.mission{grid-template-columns:minmax(0,1.15fr) minmax(0,1fr)!important;column-gap:clamp(32px,6vw,88px)!important}
.mission blockquote{grid-column:1/-1}
.motto{align-self:center;display:grid;gap:18px;padding-left:clamp(20px,3vw,40px);border-left:2px solid var(--amber)}
.motto p{font-family:var(--display);font-weight:800;font-size:clamp(28px,3vw,42px);line-height:1.08;color:var(--teal);letter-spacing:-.03em;white-space:nowrap}
.motto p em{font-style:normal;color:var(--amber)}
.motto p{color:#0A5C68}
@media (prefers-color-scheme:dark){:root:not([data-theme="light"]) .motto p{color:var(--teal)}}
:root[data-theme="dark"] .motto p{color:var(--teal)}
.motto span{font-family:var(--mono);font-size:12px;letter-spacing:.14em;text-transform:uppercase;color:var(--muted)}
@media(max-width:820px){.mission{grid-template-columns:1fr!important}.motto{padding-left:20px}}

.person{display:flex!important;flex-direction:column}
.links{display:flex;flex-wrap:wrap;gap:8px;margin-top:auto;padding-top:8px}
.links a{display:inline-flex;align-items:center;gap:6px;height:30px;padding:0 10px;border-radius:8px;border:1px solid var(--line);font-family:var(--mono);font-size:11px;letter-spacing:.04em;text-decoration:none;color:var(--muted);transition:border-color .2s,color .2s}
.links a:hover{border-color:var(--teal);color:var(--teal)}
.links svg{width:14px;height:14px;fill:currentColor;flex:none}
.links a{width:34px;height:34px;padding:0;justify-content:center;border-radius:9px}
.links a span{position:absolute;width:1px;height:1px;overflow:hidden;clip:rect(0 0 0 0)}
.links svg{width:16px!important;height:16px!important}
.links{gap:6px}

.pubs{display:grid;gap:40px}
.pub-year{display:grid;grid-template-columns:120px 1fr;gap:24px;border-top:1px solid var(--line);padding-top:24px}
.pub-year h2{font-size:32px;font-weight:800;color:var(--teal);font-variant-numeric:tabular-nums}
.pub-list{display:grid;gap:14px}
.pub{display:grid;gap:8px;padding:20px 22px;background:var(--surface);border:1px solid var(--line);border-radius:14px;text-decoration:none;color:inherit;transition:border-color .2s,transform .2s}
.pub:hover{border-color:var(--teal);transform:translateY(-2px)}
.pub h3{font-size:19px;font-weight:700;line-height:1.3;letter-spacing:-.01em}
.pub-tag{justify-self:start;font-family:var(--mono);font-size:11px;letter-spacing:.1em;text-transform:uppercase;padding:3px 9px;border-radius:999px;background:var(--teal-soft);color:var(--teal)}
.pub-au{font-size:14px;color:var(--muted)}
.pub-j{font-size:13px;font-family:var(--mono);color:var(--muted)}
.pub-j span{color:var(--teal)}
.pub-tag.abs{background:transparent;border:1px solid var(--line);color:var(--muted)}
.pub-tag.clin{background:var(--amber-soft);color:var(--amber)}
@media(max-width:640px){.pub-year{grid-template-columns:1fr;gap:12px}}
.sci-link{display:inline-flex;align-items:center;gap:10px;margin-top:6px;justify-self:start;padding:12px 20px;border-radius:999px;background:var(--teal);color:var(--ground);font-weight:600;font-size:15px;text-decoration:none;transition:transform .2s}
.sci-link:hover{transform:translateY(-2px)}

.inv{text-decoration:none;border-bottom:1px solid var(--line);transition:color .2s,border-color .2s}
.inv:hover{color:var(--teal);border-color:var(--teal)}
.partners-strip{display:grid;grid-template-columns:140px 1fr;gap:24px;align-items:center;margin-top:56px;padding-top:32px;border-top:1px solid var(--line)}
.logos{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:16px}
.logo-card{background:#fff;border:1px solid var(--line);border-radius:16px;padding:24px 28px 18px;display:grid;gap:14px;justify-items:center;transition:transform .2s,box-shadow .2s}
.logo-card:hover{transform:translateY(-2px);box-shadow:0 12px 30px -18px rgba(5,44,59,.4)}
.logo-card{grid-template-rows:88px auto;align-items:center}
.logo-card img{width:auto;max-width:100%;object-fit:contain}
.logo-card .lg-ip{height:80px}
.logo-card .lg-az{height:58px}
.logo-card small{font-family:var(--mono);font-size:11px;letter-spacing:.08em;text-transform:uppercase;color:#51656B}
@media(max-width:700px){.partners-strip{grid-template-columns:1fr}.logos{grid-template-columns:1fr}}

.mission{grid-template-columns:minmax(0,1.15fr) minmax(0,1fr)!important;column-gap:clamp(32px,6vw,88px)!important}
.mission blockquote{grid-column:1/-1}
.motto{align-self:center;display:grid;gap:18px;padding-left:clamp(20px,3vw,40px);border-left:2px solid var(--amber)}
.motto p{font-family:var(--display);font-weight:800;font-size:clamp(28px,3vw,42px);line-height:1.08;color:var(--teal);letter-spacing:-.03em;white-space:nowrap}
.motto p em{font-style:normal;color:var(--amber)}
.motto p{color:#0A5C68}
@media (prefers-color-scheme:dark){:root:not([data-theme="light"]) .motto p{color:var(--teal)}}
:root[data-theme="dark"] .motto p{color:var(--teal)}
.motto span{font-family:var(--mono);font-size:12px;letter-spacing:.14em;text-transform:uppercase;color:var(--muted)}
@media(max-width:820px){.mission{grid-template-columns:1fr!important}.motto{padding-left:20px}}

.person{display:flex!important;flex-direction:column}
.links{display:flex;flex-wrap:wrap;gap:8px;margin-top:auto;padding-top:8px}
.links a{display:inline-flex;align-items:center;gap:6px;height:30px;padding:0 10px;border-radius:8px;border:1px solid var(--line);font-family:var(--mono);font-size:11px;letter-spacing:.04em;text-decoration:none;color:var(--muted);transition:border-color .2s,color .2s}
.links a:hover{border-color:var(--teal);color:var(--teal)}
.links svg{width:14px;height:14px;fill:currentColor;flex:none}
.links a{width:34px;height:34px;padding:0;justify-content:center;border-radius:9px}
.links a span{position:absolute;width:1px;height:1px;overflow:hidden;clip:rect(0 0 0 0)}
.links svg{width:16px!important;height:16px!important}
.links{gap:6px}

.pubs{display:grid;gap:40px}
.pub-year{display:grid;grid-template-columns:120px 1fr;gap:24px;border-top:1px solid var(--line);padding-top:24px}
.pub-year h2{font-size:32px;font-weight:800;color:var(--teal);font-variant-numeric:tabular-nums}
.pub-list{display:grid;gap:14px}
.pub{display:grid;gap:8px;padding:20px 22px;background:var(--surface);border:1px solid var(--line);border-radius:14px;text-decoration:none;color:inherit;transition:border-color .2s,transform .2s}
.pub:hover{border-color:var(--teal);transform:translateY(-2px)}
.pub h3{font-size:19px;font-weight:700;line-height:1.3;letter-spacing:-.01em}
.pub-tag{justify-self:start;font-family:var(--mono);font-size:11px;letter-spacing:.1em;text-transform:uppercase;padding:3px 9px;border-radius:999px;background:var(--teal-soft);color:var(--teal)}
.pub-au{font-size:14px;color:var(--muted)}
.pub-j{font-size:13px;font-family:var(--mono);color:var(--muted)}
.pub-j span{color:var(--teal)}
.pub-tag.abs{background:transparent;border:1px solid var(--line);color:var(--muted)}
.pub-tag.clin{background:var(--amber-soft);color:var(--amber)}
@media(max-width:640px){.pub-year{grid-template-columns:1fr;gap:12px}}
.sci-link{display:inline-flex;align-items:center;gap:10px;margin-top:6px;justify-self:start;padding:12px 20px;border-radius:999px;background:var(--teal);color:var(--ground);font-weight:600;font-size:15px;text-decoration:none;transition:transform .2s}
.sci-link:hover{transform:translateY(-2px)}

.mech-head{display:grid;gap:14px;margin-top:72px}
.mech-head h3{font-size:clamp(30px,4.2vw,52px);font-weight:800;line-height:1.05;color:var(--ink)}
.mech{margin-top:28px!important;align-items:start!important}
.mech-rev{grid-template-columns:1.15fr 1fr!important}
@media(max-width:860px){.mech-rev{grid-template-columns:1fr!important}.mech-rev .micro{order:2}}
.trial a:not([href]){text-decoration:none}
.micro{margin:0;display:grid;gap:10px}
.micro img{width:100%;height:auto;max-width:100%;display:block;border-radius:20px;box-shadow:0 20px 50px -20px rgba(12,42,49,.45)}
.micro figcaption{font-family:var(--mono);font-size:12px;color:var(--muted)}
.timeline{grid-template-columns:repeat(6,1fr)}
@media(max-width:980px){.timeline{grid-template-columns:1fr 1fr 1fr;row-gap:36px}.timeline::before{display:none}}
@media(max-width:520px){.timeline{grid-template-columns:1fr}}
.item{color:inherit}
.feature{text-decoration:none;transition:transform .25s}
.feature:hover{transform:translateY(-3px)}
.feature .more{font-weight:600;color:var(--amber);position:relative}
.allnews{display:inline-flex;margin-top:22px;font-weight:600;color:var(--teal);text-decoration:none}
.allnews:hover{text-decoration:underline}
.chip.gm{background:var(--amber-soft);color:var(--amber)}

/* photos */
.person .avatar{width:100%;height:auto;aspect-ratio:1;max-width:100%;border-radius:12px;font-size:clamp(28px,3vw,40px);overflow:hidden;margin-bottom:6px;background:linear-gradient(145deg,var(--teal-soft),color-mix(in srgb,var(--teal-soft) 60%,var(--ground)))}
.avatar img{width:100%;height:100%;object-fit:cover;display:block;filter:saturate(.92)}

/* views */
.view[hidden]{display:none!important}
.page-head{background:var(--hero);color:var(--hero-ink)}
.page-head .wrap{padding-block:clamp(48px,7vw,88px) clamp(36px,5vw,56px);display:grid;gap:18px}
.page-head h1{font-size:clamp(30px,4.6vw,54px);font-weight:800;line-height:1.05;max-width:24ch}
.page-head .eyebrow{color:var(--amber)}
.back{color:var(--hero-muted);text-decoration:none;font-size:14px;font-family:var(--mono)}
.back:hover{color:var(--hero-ink)}
.article{display:grid;grid-template-columns:minmax(0,1fr) 300px;gap:clamp(32px,5vw,72px);padding-block:clamp(48px,6vw,80px)}
.prose{max-width:68ch;display:grid;gap:18px;font-size:17px}
.prose h2{font-size:22px;font-weight:700;margin-top:14px;letter-spacing:-.01em}
.prose ul{margin:0;padding-left:20px;display:grid;gap:6px}
.prose a{color:var(--teal)}
.prose .kpis{display:grid;grid-template-columns:repeat(3,1fr);gap:12px;margin-block:6px}
.prose .kpis div{background:var(--surface);border:1px solid var(--line);border-radius:12px;padding:16px}
.prose .kpis strong{display:block;font-family:var(--display);font-size:30px;font-weight:800;color:var(--teal);line-height:1.1}
.prose .kpis span{font-size:13px;color:var(--muted)}
.prose .quote{border-left:3px solid var(--amber);padding-left:18px;font-family:var(--display);font-size:20px;font-weight:600}
@media(max-width:600px){.prose .kpis{grid-template-columns:1fr}}
.aside{display:grid;gap:16px;align-content:start}
.box{background:var(--surface);border:1px solid var(--line);border-radius:16px;padding:22px;display:grid;gap:8px;font-size:14px}
.box h4{margin:0;font-family:var(--mono);font-size:11px;letter-spacing:.14em;text-transform:uppercase;color:var(--teal);font-weight:500}
.box a{color:var(--teal)}
.pager{display:flex;justify-content:space-between;gap:16px;flex-wrap:wrap;border-top:1px solid var(--line);padding-top:24px;margin-top:12px}
.pager a{text-decoration:none;font-weight:600;color:var(--teal);max-width:45%}
.pager small{display:block;font-family:var(--mono);font-weight:400;font-size:11px;color:var(--muted);letter-spacing:.1em;text-transform:uppercase}
@media(max-width:860px){.article{grid-template-columns:1fr}}
.archive{padding-block:clamp(40px,6vw,72px)}
.archive .list{max-width:860px}
.archive .item{grid-template-columns:120px 1fr}
.todo{background:var(--amber-soft);color:var(--ink);padding:1px 6px;border-radius:4px;font-family:var(--mono);font-size:.85em}

/* contact form */
.contact .grid{align-items:end}
form.cf{display:grid;grid-template-columns:1fr 1fr;gap:14px;margin-top:36px}
.cf .full{grid-column:1/-1}
.cf label{display:grid;gap:6px;font-family:var(--mono);font-size:11px;letter-spacing:.12em;text-transform:uppercase;color:var(--hero-muted)}
.cf input,.cf select,.cf textarea{font:inherit;font-family:var(--body);font-size:16px;letter-spacing:0;text-transform:none;color:var(--hero-ink);background:rgba(234,243,241,.06);border:1px solid rgba(234,243,241,.18);border-radius:10px;padding:12px 14px;width:100%}
.cf select option{color:#0F242B}
.cf textarea{min-height:130px;resize:vertical}
.cf input:focus,.cf select:focus,.cf textarea:focus{outline:none;border-color:var(--amber);background:rgba(234,243,241,.1)}
.cf .consent{display:flex;gap:10px;align-items:flex-start;text-transform:none;letter-spacing:0;font-family:var(--body);font-size:13px}
.cf .consent input{width:auto;margin-top:3px}
.cf button{justify-self:start;border:0;cursor:pointer;font:inherit}
.cf-status{grid-column:1/-1;font-size:14px;color:var(--amber);min-height:1.4em}
.hp{position:absolute;left:-9999px}
@media(max-width:600px){form.cf{grid-template-columns:1fr}}
footer a{color:var(--hero-muted)}
footer a:hover{color:var(--hero-ink)}


/* timeline — mobile vertical rail (v1.3) */
@media(max-width:520px){
  .timeline{display:block;position:relative;padding-left:26px;grid-template-columns:none}
  .timeline::before{display:block;content:"";position:absolute;left:7px;right:auto;top:8px;bottom:16px;width:2px;height:auto;background:var(--line)}
  .tl{display:block;padding:0 0 20px 0}
  .tl:last-child{padding-bottom:0}
  .tl::before{left:-26px;top:6px;width:12px;height:12px;border-width:2px}
  .tl time{font-size:17px;font-weight:800;color:var(--teal);display:block;line-height:1.2}
  .tl.hot time{color:var(--amber)}
  .tl p{font-size:14.5px;margin-top:2px}
}